After watching the full 8 hours of the "Immunology of Protection from Ebola Virus Infection" workshop (sponsored by the NIAID/NIH, FDA, BARDA, DoD, and CDC) it is abundantly clear that the Ebola vaccine efforts are sadly an expensive and near worthless joke. We say this because at best, if the vaccine designs are perfect, they will only protect those who have been exposed to the most minuscule amounts of Ebola.
The vaccine developers are clear that the proposed vaccines will be utterly overwhelmed if the person is exposed to anything more than a needle prick's worth of virus. And even at that tiny amount, the vaccine researchers are complaining that its too much virus; they want 1/100 of a needle prick's worth of virus, at maximum, to be the challenge standard for the vaccine.
As such, the vaccines in development are not to protect the public; at best, they are designed to offer a modicum of protection to Ebola researchers who may develop small holes in their spacesuits as they are working in the their Bio Safety Level 4 Laboratories. These vaccines would likely NOT have protected either of the Dallas nurses who were infected with Ebola in the course of treating Thomas Duncan.
The researchers at the conference are aware of the fact that these vaccines will offer no real individual protection. In fact it was indicated at the conference that if all goes well and the vaccine is given to a large enough segment of the public, that maybe the vaccines might slightly reduce the virus reproduction number, ie every infected person only makes 2 other people sick instead of 3.
Frankly thats a very large safety gamble to force an experimental vaccine on the population for the outside possibility that it might ever so slightly reduce the reproduction number of the virus. Its pretty clear now why the Government has declared that no one working on the vaccines ,or forcing those vaccines on the public can be held civilly or criminally liable for their work.
At this point, its becoming very clear that the greatest return on research dollar investment is on post exposure treatment with Antibodies and Antivirals; the vaccine work is a joke.
Immunology of Protection from Ebola Virus Infection A workshop sponsored by the NIAID/NIH, FDA, BARDA, DoD, and CDC
ACTION: Notice of Declaration under the Public Readiness and Emergency Preparedness Act
NIH: Airborne Ebola Infectious Down To Extinction Levels